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active ras detection kit  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc active ras detection kit
    Active Ras Detection Kit, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 95/100, based on 133 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/active+ras+detection+kit/pm41620418-294-6-10?v=Cell+Signaling+Technology+Inc
    Average 95 stars, based on 133 article reviews
    active ras detection kit - by Bioz Stars, 2026-07
    95/100 stars

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    active ras detection kit  (Cell Signaling Technology Inc)
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    ras activation assay kit  (Cell Signaling Technology Inc)
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    A . Western blots showing levels of pERK, total ERK, pAKT, total AKT, non-phospho-β-catenin, total β-catenin, LC3A/B, cleaved PARP, and cleaved caspase 3 in 2838c3- f -luc tumors after vehicle or ADT-030 treatment. B-G . Bar graphs representing the quantifications of western blots from panel A: pERK ( B ), p-AKT ( C ), non-phospho-β-catenin ( D ), LC3A/B ( E ), cleaved PARP ( F ), and cleaved caspase 3 ( G ) in tumor tissues after ADT-030 vs. vehicle treatments. Welch t -test was used for statistical analysis. H . The inhibitory effect of ADT-030 on <t>activated</t> <t>(GTP-bound)</t> <t>RAS</t> in tumors after vehicle or ADT-030 treatments was assessed by RAS-RBD pull-down assay. I . Representative Ki-67 IHC results in tumors after vehicle or ADT-030 treatment. J-L . Representative IF images of LC3A/B (J) , vimentin (K) , and E-Cadherin (L) in tumors after vehicle or ADT-030 treatment. M . Bar graph representing the quantification of IHC staining for KI-67. N-P . Dot-plot graphs representing the IF quantifications of LC3A/B (N) , vimentin (O) , and E-Cadherin (P) in tumors after vehicle or ADT-030 treatment. Welch t-test was used for statistical analysis. ns, non-significant, ∗p < 0.05, ∗∗p < 0.01, and ∗∗∗∗p < 0.0001.
    Ras Activation Assay Kit, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    active ras detection kit 159  (Cell Signaling Technology Inc)
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    A . Western blots showing levels of pERK, total ERK, pAKT, total AKT, non-phospho-β-catenin, total β-catenin, LC3A/B, cleaved PARP, and cleaved caspase 3 in 2838c3- f -luc tumors after vehicle or ADT-030 treatment. B-G . Bar graphs representing the quantifications of western blots from panel A: pERK ( B ), p-AKT ( C ), non-phospho-β-catenin ( D ), LC3A/B ( E ), cleaved PARP ( F ), and cleaved caspase 3 ( G ) in tumor tissues after ADT-030 vs. vehicle treatments. Welch t -test was used for statistical analysis. H . The inhibitory effect of ADT-030 on <t>activated</t> <t>(GTP-bound)</t> <t>RAS</t> in tumors after vehicle or ADT-030 treatments was assessed by RAS-RBD pull-down assay. I . Representative Ki-67 IHC results in tumors after vehicle or ADT-030 treatment. J-L . Representative IF images of LC3A/B (J) , vimentin (K) , and E-Cadherin (L) in tumors after vehicle or ADT-030 treatment. M . Bar graph representing the quantification of IHC staining for KI-67. N-P . Dot-plot graphs representing the IF quantifications of LC3A/B (N) , vimentin (O) , and E-Cadherin (P) in tumors after vehicle or ADT-030 treatment. Welch t-test was used for statistical analysis. ns, non-significant, ∗p < 0.05, ∗∗p < 0.01, and ∗∗∗∗p < 0.0001.
    Active Ras Detection Kit 159, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Average 95 stars, based on 1 article reviews
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    ras detection kit  (Cell Signaling Technology Inc)
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    Cell Signaling Technology Inc ras detection kit
    A . Western blots showing levels of pERK, total ERK, pAKT, total AKT, non-phospho-β-catenin, total β-catenin, LC3A/B, cleaved PARP, and cleaved caspase 3 in 2838c3- f -luc tumors after vehicle or ADT-030 treatment. B-G . Bar graphs representing the quantifications of western blots from panel A: pERK ( B ), p-AKT ( C ), non-phospho-β-catenin ( D ), LC3A/B ( E ), cleaved PARP ( F ), and cleaved caspase 3 ( G ) in tumor tissues after ADT-030 vs. vehicle treatments. Welch t -test was used for statistical analysis. H . The inhibitory effect of ADT-030 on <t>activated</t> <t>(GTP-bound)</t> <t>RAS</t> in tumors after vehicle or ADT-030 treatments was assessed by RAS-RBD pull-down assay. I . Representative Ki-67 IHC results in tumors after vehicle or ADT-030 treatment. J-L . Representative IF images of LC3A/B (J) , vimentin (K) , and E-Cadherin (L) in tumors after vehicle or ADT-030 treatment. M . Bar graph representing the quantification of IHC staining for KI-67. N-P . Dot-plot graphs representing the IF quantifications of LC3A/B (N) , vimentin (O) , and E-Cadherin (P) in tumors after vehicle or ADT-030 treatment. Welch t-test was used for statistical analysis. ns, non-significant, ∗p < 0.05, ∗∗p < 0.01, and ∗∗∗∗p < 0.0001.
    Ras Detection Kit, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/active+ras+detection+kit/pm41208497-107-4-8?v=Cell+Signaling+Technology+Inc
    Average 95 stars, based on 1 article reviews
    ras detection kit - by Bioz Stars, 2026-07
    95/100 stars
    		  Buy from Supplier

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    A . Western blots showing levels of pERK, total ERK, pAKT, total AKT, non-phospho-β-catenin, total β-catenin, LC3A/B, cleaved PARP, and cleaved caspase 3 in 2838c3- f -luc tumors after vehicle or ADT-030 treatment. B-G . Bar graphs representing the quantifications of western blots from panel A: pERK ( B ), p-AKT ( C ), non-phospho-β-catenin ( D ), LC3A/B ( E ), cleaved PARP ( F ), and cleaved caspase 3 ( G ) in tumor tissues after ADT-030 vs. vehicle treatments. Welch t -test was used for statistical analysis. H . The inhibitory effect of ADT-030 on activated (GTP-bound) RAS in tumors after vehicle or ADT-030 treatments was assessed by RAS-RBD pull-down assay. I . Representative Ki-67 IHC results in tumors after vehicle or ADT-030 treatment. J-L . Representative IF images of LC3A/B (J) , vimentin (K) , and E-Cadherin (L) in tumors after vehicle or ADT-030 treatment. M . Bar graph representing the quantification of IHC staining for KI-67. N-P . Dot-plot graphs representing the IF quantifications of LC3A/B (N) , vimentin (O) , and E-Cadherin (P) in tumors after vehicle or ADT-030 treatment. Welch t-test was used for statistical analysis. ns, non-significant, ∗p < 0.05, ∗∗p < 0.01, and ∗∗∗∗p < 0.0001.

    Journal: bioRxiv

    Article Title: ADT-030, a novel PDE10 inhibitor, demonstrates potent antitumor activity in pancreatic ductal adenocarcinoma

    doi: 10.64898/2026.02.11.705411

    Figure Lengend Snippet: A . Western blots showing levels of pERK, total ERK, pAKT, total AKT, non-phospho-β-catenin, total β-catenin, LC3A/B, cleaved PARP, and cleaved caspase 3 in 2838c3- f -luc tumors after vehicle or ADT-030 treatment. B-G . Bar graphs representing the quantifications of western blots from panel A: pERK ( B ), p-AKT ( C ), non-phospho-β-catenin ( D ), LC3A/B ( E ), cleaved PARP ( F ), and cleaved caspase 3 ( G ) in tumor tissues after ADT-030 vs. vehicle treatments. Welch t -test was used for statistical analysis. H . The inhibitory effect of ADT-030 on activated (GTP-bound) RAS in tumors after vehicle or ADT-030 treatments was assessed by RAS-RBD pull-down assay. I . Representative Ki-67 IHC results in tumors after vehicle or ADT-030 treatment. J-L . Representative IF images of LC3A/B (J) , vimentin (K) , and E-Cadherin (L) in tumors after vehicle or ADT-030 treatment. M . Bar graph representing the quantification of IHC staining for KI-67. N-P . Dot-plot graphs representing the IF quantifications of LC3A/B (N) , vimentin (O) , and E-Cadherin (P) in tumors after vehicle or ADT-030 treatment. Welch t-test was used for statistical analysis. ns, non-significant, ∗p < 0.05, ∗∗p < 0.01, and ∗∗∗∗p < 0.0001.

    Article Snippet: RAS activation (RAS-GTP) levels were measured using the active RAS activation assay kit (Cell Signaling Technology, Cat# 8821).

    Techniques: Western Blot, Pull Down Assay, Immunohistochemistry